Drug resistance in cancer
نویسندگان
چکیده
منابع مشابه
The Role of Epigenetics in Cancer Drug Resistance
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...
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Resistance to chemotherapy drugs is a major problem in cancer treatment. Scientific advances made in the last two decades have resulted in the identification of genes and molecular signaling mechanisms that contribute to drug resistance. This has resulted in a better understanding of the biology of cancer cells and the way these cells adapt or undergo subtle molecular changes thereby protecting...
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Department of Patology and Laboratory of Molecular Pathology, Laboratory of Experimental Medicine, Department of Pediatrics, Department of Tuberculosis and Respiratory Diseases and 1st. Surgical department Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic, Department of Pathology, The Chaim Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Te...
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Chemoresistance is one of the main obstacles to the success of cancer treatment and one of the most important causes of death in patients. In the last decade, progress in high-throughput technologies, including microarray, sequencing, and bioinformatics has greatly resulted in cancer gene profiling and identification of biomarkers for cancer prognosis and prediction. This has greatly improved t...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2005
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6602821